2025 Conference USA Leaders Passes Defended - Games in November Only through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 3 | 7 | 12 | 19 | 6.33 |
| 2 | New Mexico State | 4 | 6 | 14 | 20 | 5.00 |
| 2 | Louisiana Tech | 3 | 6 | 7 | 13 | 4.33 |
| 4 | Middle Tennessee State | 3 | 4 | 13 | 17 | 5.67 |
| 4 | Kennesaw State | 3 | 4 | 10 | 14 | 4.67 |
| 6 | FIU | 3 | 3 | 19 | 22 | 7.33 |
| 6 | Sam Houston State | 3 | 3 | 11 | 14 | 4.67 |
| 6 | Delaware | 4 | 3 | 9 | 12 | 3.00 |
| 9 | Western Kentucky | 3 | 2 | 23 | 25 | 8.33 |
| 9 | Liberty | 4 | 2 | 14 | 16 | 4.00 |
| 9 | UTEP | 3 | 2 | 6 | 8 | 2.67 |
| 12 | Missouri State | 3 | 1 | 14 | 15 | 5.00 |