2025 Conference USA Leaders Passes Defended - Games vs. Unranked Teams Only (AP Poll) through 10/08/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 10 | 30 | 40 | 10.00 |
| 2 | Western Kentucky | 6 | 5 | 24 | 29 | 4.83 |
| 2 | New Mexico State | 5 | 5 | 16 | 21 | 4.20 |
| 2 | Liberty | 6 | 5 | 16 | 21 | 3.50 |
| 5 | FIU | 5 | 4 | 20 | 24 | 4.80 |
| 5 | Delaware | 5 | 4 | 14 | 18 | 3.60 |
| 7 | Missouri State | 6 | 3 | 22 | 25 | 4.17 |
| 7 | Middle Tennessee State | 6 | 3 | 19 | 22 | 3.67 |
| 7 | Jacksonville State | 5 | 3 | 17 | 20 | 4.00 |
| 10 | UTEP | 6 | 2 | 21 | 23 | 3.83 |
| 10 | Sam Houston State | 5 | 2 | 16 | 18 | 3.60 |
| 12 | Kennesaw State | 4 | 1 | 17 | 18 | 4.50 |