2025 Conference USA Leaders Passes Defended - Games vs. FBS Teams With Non-Winning Record Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 3 | 8 | 25 | 33 | 11.00 |
| 2 | Western Kentucky | 6 | 6 | 26 | 32 | 5.33 |
| 3 | Missouri State | 4 | 5 | 22 | 27 | 6.75 |
| 4 | Liberty | 4 | 3 | 18 | 21 | 5.25 |
| 4 | Jacksonville State | 6 | 2 | 19 | 21 | 3.50 |
| 6 | FIU | 3 | 4 | 15 | 19 | 6.33 |
| 7 | Delaware | 4 | 3 | 15 | 18 | 4.50 |
| 8 | New Mexico State | 3 | 5 | 11 | 16 | 5.33 |
| 9 | Kennesaw State | 3 | 1 | 14 | 15 | 5.00 |
| 10 | Middle Tennessee State | 4 | 4 | 8 | 12 | 3.00 |
| 10 | UTEP | 4 | 0 | 12 | 12 | 3.00 |
| 12 | Sam Houston State | 2 | 1 | 3 | 4 | 2.00 |