2025 Conference USA Leaders Passes Defended - Games vs. Unranked Teams Only (AP Poll) through 12/13/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 12 | 20 | 63 | 83 | 6.92 |
| 2 | New Mexico State | 12 | 15 | 48 | 63 | 5.25 |
| 2 | FIU | 12 | 12 | 51 | 63 | 5.25 |
| 4 | Western Kentucky | 12 | 8 | 53 | 61 | 5.08 |
| 5 | Kennesaw State | 12 | 8 | 49 | 57 | 4.75 |
| 6 | Jacksonville State | 13 | 12 | 44 | 56 | 4.31 |
| 7 | Missouri State | 11 | 8 | 47 | 55 | 5.00 |
| 8 | Middle Tennessee State | 12 | 10 | 41 | 51 | 4.25 |
| 9 | Delaware | 12 | 13 | 32 | 45 | 3.75 |
| 10 | Liberty | 11 | 6 | 34 | 40 | 3.64 |
| 11 | UTEP | 11 | 4 | 35 | 39 | 3.55 |
| 12 | Sam Houston State | 11 | 8 | 30 | 38 | 3.45 |