2025 Conference USA Leaders Passes Defended - Games vs. Unranked Teams Only (AP Poll) through 11/22/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 11 | 19 | 58 | 77 | 7.00 |
| 2 | FIU | 11 | 10 | 49 | 59 | 5.36 |
| 2 | Western Kentucky | 11 | 8 | 51 | 59 | 5.36 |
| 4 | New Mexico State | 10 | 13 | 41 | 54 | 5.40 |
| 5 | Kennesaw State | 10 | 7 | 43 | 50 | 5.00 |
| 5 | Jacksonville State | 11 | 11 | 39 | 50 | 4.55 |
| 7 | Missouri State | 9 | 7 | 42 | 49 | 5.44 |
| 8 | Middle Tennessee State | 11 | 8 | 37 | 45 | 4.09 |
| 9 | Liberty | 10 | 6 | 32 | 38 | 3.80 |
| 9 | Delaware | 11 | 8 | 30 | 38 | 3.45 |
| 11 | UTEP | 10 | 4 | 32 | 36 | 3.60 |
| 12 | Sam Houston State | 10 | 7 | 28 | 35 | 3.50 |