2025 Conference USA Leaders Passes Defended - Games in November Only through 12/13/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 4 | 2 | 25 | 27 | 6.75 |
| 2 | FIU | 4 | 5 | 21 | 26 | 6.50 |
| 2 | New Mexico State | 5 | 6 | 20 | 26 | 5.20 |
| 4 | Middle Tennessee State | 4 | 6 | 17 | 23 | 5.75 |
| 5 | Jacksonville State | 4 | 8 | 14 | 22 | 5.50 |
| 6 | Louisiana Tech | 4 | 7 | 12 | 19 | 4.75 |
| 6 | Delaware | 5 | 8 | 11 | 19 | 3.80 |
| 8 | Liberty | 5 | 2 | 16 | 18 | 3.60 |
| 9 | Sam Houston State | 4 | 4 | 13 | 17 | 4.25 |
| 9 | Kennesaw State | 4 | 4 | 13 | 17 | 4.25 |
| 11 | Missouri State | 4 | 1 | 15 | 16 | 4.00 |
| 12 | UTEP | 4 | 2 | 9 | 11 | 2.75 |