2025 Conference USA Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 10/08/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 402 | 1059 | 280 | 1461 | 5.22 | 365.3 |
| 2 | Delaware | 4 | 573 | 1047 | 267 | 1620 | 6.07 | 405.0 |
| 3 | FIU | 4 | 634 | 1131 | 279 | 1765 | 6.33 | 441.3 |
| 4 | Kennesaw State | 4 | 690 | 1029 | 290 | 1719 | 5.93 | 429.8 |
| 5 | New Mexico State | 4 | 695 | 1043 | 296 | 1738 | 5.87 | 434.5 |
| 6 | Sam Houston State | 5 | 742 | 1542 | 345 | 2284 | 6.62 | 456.8 |
| 7 | Jacksonville State | 4 | 751 | 992 | 274 | 1743 | 6.36 | 435.8 |
| 8 | Middle Tennessee State | 5 | 770 | 1165 | 306 | 1935 | 6.32 | 387.0 |
| 9 | Missouri State | 5 | 836 | 1312 | 320 | 2148 | 6.71 | 429.6 |
| 10 | UTEP | 5 | 858 | 876 | 350 | 1734 | 4.95 | 346.8 |
| 11 | Liberty | 5 | 997 | 793 | 320 | 1790 | 5.59 | 358.0 |
| 12 | Western Kentucky | 5 | 1022 | 1089 | 342 | 2111 | 6.17 | 422.2 |