2025 Conference USA Leaders Total Defense - Games vs. Unranked Teams Only (AP Poll) through 10/08/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Liberty | 6 | 1181 | 925 | 383 | 2106 | 5.50 | 351.0 |
| 2 | Kennesaw State | 4 | 456 | 964 | 286 | 1420 | 4.97 | 355.0 |
| 3 | Louisiana Tech | 4 | 400 | 967 | 280 | 1367 | 4.88 | 341.8 |
| 4 | Jacksonville State | 5 | 843 | 1133 | 342 | 1976 | 5.78 | 395.2 |
| 5 | UTEP | 6 | 934 | 1171 | 426 | 2105 | 4.94 | 350.8 |
| 6 | Western Kentucky | 6 | 1175 | 1194 | 414 | 2369 | 5.72 | 394.8 |
| 7 | Delaware | 5 | 773 | 1196 | 334 | 1969 | 5.90 | 393.8 |
| 8 | New Mexico State | 5 | 763 | 1230 | 364 | 1993 | 5.48 | 398.6 |
| 9 | Middle Tennessee State | 6 | 920 | 1358 | 380 | 2278 | 5.99 | 379.7 |
| 10 | FIU | 5 | 739 | 1372 | 348 | 2111 | 6.07 | 422.2 |
| 11 | Missouri State | 6 | 907 | 1462 | 377 | 2369 | 6.28 | 394.8 |
| 12 | Sam Houston State | 5 | 742 | 1542 | 345 | 2284 | 6.62 | 456.8 |