2025 Conference USA Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 10/08/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 1 | 128 | 237 | 75 | 365 | 4.87 | 365.0 |
| 2 | Kennesaw State | 1 | 313 | 280 | 67 | 593 | 8.85 | 593.0 |