2025 Conference USA Leaders Total Defense - Games in October Only through 11/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Liberty | 2 | 202 | 353 | 127 | 555 | 4.37 | 277.5 |
| 2 | Missouri State | 3 | 283 | 705 | 198 | 988 | 4.99 | 329.3 |
| 3 | New Mexico State | 3 | 309 | 706 | 201 | 1015 | 5.05 | 338.3 |
| 4 | Jacksonville State | 3 | 268 | 793 | 191 | 1061 | 5.55 | 353.7 |
| 5 | Middle Tennessee State | 3 | 290 | 774 | 216 | 1064 | 4.93 | 354.7 |
| 6 | UTEP | 3 | 469 | 636 | 230 | 1105 | 4.80 | 368.3 |
| 7 | Delaware | 3 | 466 | 644 | 203 | 1110 | 5.47 | 370.0 |
| 8 | Kennesaw State | 3 | 493 | 625 | 221 | 1118 | 5.06 | 372.7 |
| 9 | Louisiana Tech | 3 | 519 | 724 | 208 | 1243 | 5.98 | 414.3 |
| 10 | Western Kentucky | 3 | 479 | 858 | 233 | 1337 | 5.74 | 445.7 |
| 11 | FIU | 4 | 686 | 1049 | 253 | 1735 | 6.86 | 433.8 |
| 12 | Sam Houston State | 4 | 1066 | 841 | 257 | 1907 | 7.42 | 476.8 |