2022 Conference USA Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 1 | 135 | 280 | 76 | 415 | 5.46 | 415.0 |
| 2 | Louisiana Tech | 1 | 280 | 241 | 74 | 521 | 7.04 | 521.0 |
| 3 | Rice | 1 | 208 | 330 | 58 | 538 | 9.28 | 538.0 |
| 4 | Charlotte | 1 | 295 | 250 | 66 | 545 | 8.26 | 545.0 |
| 5 | UAB | 1 | 269 | 299 | 72 | 568 | 7.89 | 568.0 |
| 6 | UTSA | 2 | 338 | 274 | 125 | 612 | 4.90 | 306.0 |