2025 Conference USA Leaders Total Defense - Games vs. FBS Teams With Non-Winning Record Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 1 | 191 | 83 | 57 | 274 | 4.81 | 274.0 |
| 2 | Middle Tennessee State | 1 | 203 | 166 | 60 | 369 | 6.15 | 369.0 |
| 3 | New Mexico State | 1 | 141 | 234 | 77 | 375 | 4.87 | 375.0 |
| 4 | Western Kentucky | 1 | 173 | 209 | 61 | 382 | 6.26 | 382.0 |
| 5 | Liberty | 1 | 338 | 52 | 62 | 390 | 6.29 | 390.0 |
| 6 | FIU | 1 | 135 | 343 | 82 | 478 | 5.83 | 478.0 |
| 7 | Delaware | 2 | 305 | 614 | 141 | 919 | 6.52 | 459.5 |
| 8 | Jacksonville State | 2 | 418 | 526 | 132 | 944 | 7.15 | 472.0 |