2025 Conference USA Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 11/01/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 1 | 30 | 233 | 7.77 | 6 | 30.00 | 233.00 |
| 2 | Kennesaw State | 1 | 39 | 313 | 8.03 | 3 | 39.00 | 313.00 |
| 3 | Sam Houston State | 1 | 41 | 264 | 6.44 | 4 | 41.00 | 264.00 |
| 4 | UTEP | 1 | 56 | 226 | 4.04 | 2 | 56.00 | 226.00 |