2025 Conference USA Leaders Total Defense - Games Lost Only through 12/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 5 | 603 | 1204 | 350 | 1807 | 5.16 | 361.4 |
| 2 | Jacksonville State | 5 | 826 | 1099 | 345 | 1925 | 5.58 | 385.0 |
| 3 | UTEP | 10 | 1799 | 2128 | 724 | 3927 | 5.42 | 392.7 |
| 4 | Liberty | 8 | 1687 | 1532 | 540 | 3219 | 5.96 | 402.4 |
| 5 | Middle Tennessee State | 9 | 1352 | 2316 | 615 | 3668 | 5.96 | 407.6 |
| 6 | FIU | 5 | 919 | 1235 | 319 | 2154 | 6.75 | 430.8 |
| 7 | New Mexico State | 8 | 1454 | 2026 | 585 | 3480 | 5.95 | 435.0 |
| 8 | Delaware | 6 | 1177 | 1437 | 393 | 2614 | 6.65 | 435.7 |
| 9 | Western Kentucky | 4 | 975 | 829 | 280 | 1804 | 6.44 | 451.0 |
| 10 | Kennesaw State | 3 | 695 | 697 | 198 | 1392 | 7.03 | 464.0 |
| 11 | Sam Houston State | 10 | 2208 | 2687 | 675 | 4895 | 7.25 | 489.5 |
| 12 | Missouri State | 5 | 1060 | 1436 | 338 | 2496 | 7.38 | 499.2 |