2025 Conference USA Leaders Total Defense - Games Lost Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Liberty | 2 | 496 | 198 | 130 | 694 | 5.34 | 347.0 |
| 2 | UTEP | 2 | 353 | 347 | 142 | 700 | 4.93 | 350.0 |
| 3 | Louisiana Tech | 1 | 128 | 237 | 75 | 365 | 4.87 | 365.0 |
| 4 | Middle Tennessee State | 2 | 303 | 476 | 132 | 779 | 5.90 | 389.5 |
| 5 | Delaware | 1 | 130 | 268 | 70 | 398 | 5.69 | 398.0 |
| 6 | FIU | 1 | 209 | 200 | 64 | 409 | 6.39 | 409.0 |
| 7 | Jacksonville State | 2 | 327 | 505 | 136 | 832 | 6.12 | 416.0 |
| 8 | Sam Houston State | 3 | 383 | 944 | 219 | 1327 | 6.06 | 442.3 |
| 9 | Kennesaw State | 2 | 443 | 498 | 142 | 941 | 6.63 | 470.5 |
| 10 | Western Kentucky | 1 | 307 | 201 | 63 | 508 | 8.06 | 508.0 |
| 11 | Missouri State | 2 | 400 | 645 | 127 | 1045 | 8.23 | 522.5 |
| 12 | New Mexico State | 1 | 353 | 221 | 85 | 574 | 6.75 | 574.0 |