2025 Conference USA Leaders Rushing Defense - Games vs. FBS Teams With Winning Record Only through 10/08/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Middle Tennessee State | 1 | 31 | 157 | 5.06 | 0 | 31.00 | 157.00 |
| 2 | Louisiana Tech | 3 | 86 | 276 | 3.21 | 1 | 28.67 | 92.00 |
| 3 | Jacksonville State | 2 | 87 | 333 | 3.83 | 3 | 43.50 | 166.50 |
| 3 | Liberty | 2 | 87 | 445 | 5.11 | 3 | 43.50 | 222.50 |
| 3 | New Mexico State | 2 | 103 | 485 | 4.71 | 3 | 51.50 | 242.50 |
| 6 | Delaware | 2 | 58 | 283 | 4.88 | 4 | 29.00 | 141.50 |
| 6 | Kennesaw State | 2 | 86 | 443 | 5.15 | 4 | 43.00 | 221.50 |
| 8 | FIU | 3 | 95 | 499 | 5.25 | 5 | 31.67 | 166.33 |
| 8 | Western Kentucky | 2 | 76 | 428 | 5.63 | 5 | 38.00 | 214.00 |
| 10 | UTEP | 4 | 173 | 698 | 4.03 | 7 | 43.25 | 174.50 |
| 11 | Sam Houston State | 5 | 174 | 742 | 4.26 | 10 | 34.80 | 148.40 |
| 12 | Missouri State | 3 | 93 | 559 | 6.01 | 11 | 31.00 | 186.33 |