2025 Conference USA Leaders Rushing Defense - Games at Home Only through 11/01/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | New Mexico State | 4 | 130 | 404 | 3.11 | 1 | 32.50 | 101.00 |
| 2 | Jacksonville State | 3 | 94 | 325 | 3.46 | 4 | 31.33 | 108.33 |
| 2 | Louisiana Tech | 5 | 167 | 683 | 4.09 | 4 | 33.40 | 136.60 |
| 2 | Western Kentucky | 5 | 172 | 848 | 4.93 | 4 | 34.40 | 169.60 |
| 5 | Kennesaw State | 5 | 186 | 597 | 3.21 | 5 | 37.20 | 119.40 |
| 5 | UTEP | 4 | 174 | 581 | 3.34 | 5 | 43.50 | 145.25 |
| 7 | Missouri State | 4 | 123 | 512 | 4.16 | 6 | 30.75 | 128.00 |
| 7 | Middle Tennessee State | 4 | 180 | 548 | 3.04 | 6 | 45.00 | 137.00 |
| 7 | Delaware | 4 | 121 | 586 | 4.84 | 6 | 30.25 | 146.50 |
| 7 | FIU | 4 | 133 | 594 | 4.47 | 6 | 33.25 | 148.50 |
| 7 | Liberty | 4 | 138 | 633 | 4.59 | 6 | 34.50 | 158.25 |
| 12 | Sam Houston State | 3 | 130 | 700 | 5.38 | 8 | 43.33 | 233.33 |