2025 National Leaders Passes Defended - Games in December/January Only through 12/24/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oregon | 1 | 0 | 11 | 11 | 11.00 |
| 2 | James Madison | 2 | 2 | 10 | 12 | 6.00 |
| 2 | Western Michigan | 2 | 2 | 10 | 12 | 6.00 |
| 4 | Alabama | 2 | 1 | 9 | 10 | 5.00 |
| 5 | Jacksonville State | 2 | 2 | 8 | 10 | 5.00 |
| 5 | Western Kentucky | 1 | 1 | 8 | 9 | 9.00 |
| 7 | Tulane | 2 | 3 | 7 | 10 | 5.00 |
| 7 | Duke | 1 | 2 | 7 | 9 | 9.00 |
| 7 | BYU | 1 | 0 | 7 | 7 | 7.00 |
| 7 | Boise State | 2 | 0 | 7 | 7 | 3.50 |
| 11 | Washington | 1 | 5 | 6 | 11 | 11.00 |
| 11 | Georgia | 1 | 1 | 6 | 7 | 7.00 |
| 11 | Ole Miss | 1 | 1 | 6 | 7 | 7.00 |
| 11 | Troy | 2 | 1 | 6 | 7 | 3.50 |
| 11 | Missouri State | 1 | 0 | 6 | 6 | 6.00 |
| 16 | Texas Tech | 1 | 2 | 5 | 7 | 7.00 |
| 17 | Utah State | 1 | 3 | 4 | 7 | 7.00 |
| 17 | Southern Miss | 1 | 2 | 4 | 6 | 6.00 |
| 17 | Kennesaw State | 2 | 2 | 4 | 6 | 3.00 |
| 17 | Delaware | 1 | 1 | 4 | 5 | 5.00 |
| 17 | NC State | 1 | 1 | 4 | 5 | 5.00 |
| 17 | Washington State | 1 | 1 | 4 | 5 | 5.00 |
| 17 | Arkansas State | 1 | 0 | 4 | 4 | 4.00 |
| 17 | Hawaii | 1 | 0 | 4 | 4 | 4.00 |
| 17 | Louisiana | 1 | 0 | 4 | 4 | 4.00 |
| 26 | Old Dominion | 1 | 4 | 3 | 7 | 7.00 |
| 26 | Louisville | 1 | 0 | 3 | 3 | 3.00 |
| 26 | Memphis | 1 | 0 | 3 | 3 | 3.00 |
| 26 | Toledo | 1 | 0 | 3 | 3 | 3.00 |
| 30 | Miami (FL) | 1 | 2 | 2 | 4 | 4.00 |
| 30 | Indiana | 1 | 1 | 2 | 3 | 3.00 |
| 30 | Ohio State | 1 | 1 | 2 | 3 | 3.00 |
| 30 | Ohio | 1 | 1 | 2 | 3 | 3.00 |
| 30 | UNLV | 2 | 1 | 2 | 3 | 1.50 |
| 30 | Miami (OH) | 1 | 0 | 2 | 2 | 2.00 |
| 30 | Oklahoma | 1 | 0 | 2 | 2 | 2.00 |
| 30 | USF | 1 | 0 | 2 | 2 | 2.00 |
| 30 | Texas A&M | 1 | 0 | 2 | 2 | 2.00 |
| 39 | Army | 1 | 1 | 1 | 2 | 2.00 |
| 39 | Navy | 1 | 1 | 1 | 2 | 2.00 |
| 39 | Virginia | 1 | 1 | 1 | 2 | 2.00 |
| 39 | California | 1 | 0 | 1 | 1 | 1.00 |