2025 Big 12 Conference Leaders Passes Defended - Games Won Only through 11/08/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | BYU | 8 | 12 | 25 | 37 | 4.63 |
| 2 | Texas Tech | 9 | 11 | 46 | 57 | 6.33 |
| 3 | Arizona | 6 | 9 | 29 | 38 | 6.33 |
| 3 | TCU | 6 | 9 | 21 | 30 | 5.00 |
| 5 | Houston | 8 | 8 | 35 | 43 | 5.38 |
| 5 | Iowa State | 6 | 8 | 22 | 30 | 5.00 |
| 7 | Baylor | 5 | 7 | 21 | 28 | 5.60 |
| 8 | Arizona State | 6 | 6 | 33 | 39 | 6.50 |
| 8 | Utah | 7 | 6 | 29 | 35 | 5.00 |
| 8 | Kansas State | 4 | 6 | 24 | 30 | 7.50 |
| 11 | UCF | 4 | 4 | 19 | 23 | 5.75 |
| 12 | Kansas | 5 | 3 | 19 | 22 | 4.40 |
| 12 | West Virginia | 4 | 3 | 15 | 18 | 4.50 |
| 14 | Colorado | 3 | 2 | 15 | 17 | 5.67 |
| 15 | Cincinnati | 7 | 1 | 23 | 24 | 3.43 |
| 15 | Oklahoma State | 1 | 1 | 2 | 3 | 3.00 |