2025 American Conference Leaders Passes Defended - Games vs. FBS non-Power 5 Conference Teams Only through 01/19/2026
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 11 | 9 | 43 | 52 | 4.73 |
| 2 | Memphis | 10 | 8 | 39 | 47 | 4.70 |
| 3 | USF | 10 | 10 | 35 | 45 | 4.50 |
| 4 | North Texas | 12 | 11 | 32 | 43 | 3.58 |
| 5 | Tulane | 10 | 10 | 31 | 41 | 4.10 |
| 5 | Rice | 11 | 3 | 31 | 34 | 3.09 |
| 7 | Florida Atlantic | 10 | 3 | 28 | 31 | 3.10 |
| 8 | East Carolina | 9 | 8 | 27 | 35 | 3.89 |
| 9 | Navy | 11 | 6 | 25 | 31 | 2.82 |
| 10 | Army | 11 | 7 | 24 | 31 | 2.82 |
| 10 | Temple | 9 | 5 | 24 | 29 | 3.22 |
| 12 | UAB | 10 | 3 | 21 | 24 | 2.40 |
| 13 | Tulsa | 9 | 6 | 20 | 26 | 2.89 |
| 14 | Charlotte | 9 | 6 | 18 | 24 | 2.67 |