2025 American Conference Leaders Passes Defended - Games vs. Conference Teams Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 5 | 6 | 20 | 26 | 5.20 |
| 2 | UTSA | 4 | 4 | 18 | 22 | 5.50 |
| 2 | Navy | 6 | 4 | 18 | 22 | 3.67 |
| 4 | Rice | 5 | 2 | 15 | 17 | 3.40 |
| 5 | USF | 4 | 6 | 14 | 20 | 5.00 |
| 6 | Tulane | 4 | 1 | 13 | 14 | 3.50 |
| 7 | North Texas | 5 | 4 | 12 | 16 | 3.20 |
| 7 | Temple | 5 | 4 | 12 | 16 | 3.20 |
| 7 | Tulsa | 5 | 4 | 12 | 16 | 3.20 |
| 7 | Army | 5 | 3 | 12 | 15 | 3.00 |
| 11 | East Carolina | 4 | 1 | 10 | 11 | 2.75 |
| 12 | Florida Atlantic | 5 | 0 | 9 | 9 | 1.80 |
| 13 | Charlotte | 5 | 3 | 5 | 8 | 1.60 |
| 14 | UAB | 4 | 2 | 4 | 6 | 1.50 |