2025 American Conference Leaders Passes Defended - Games Won Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 8 | 11 | 37 | 48 | 6.00 |
| 2 | Tulane | 6 | 6 | 25 | 31 | 5.17 |
| 3 | Navy | 7 | 4 | 22 | 26 | 3.71 |
| 4 | UTSA | 4 | 6 | 20 | 26 | 6.50 |
| 5 | Rice | 4 | 1 | 19 | 20 | 5.00 |
| 6 | Temple | 5 | 5 | 18 | 23 | 4.60 |
| 7 | USF | 6 | 8 | 17 | 25 | 4.17 |
| 7 | North Texas | 8 | 8 | 17 | 25 | 3.13 |
| 9 | East Carolina | 5 | 3 | 16 | 19 | 3.80 |
| 10 | UAB | 3 | 1 | 13 | 14 | 4.67 |
| 11 | Army | 4 | 4 | 12 | 16 | 4.00 |
| 12 | Florida Atlantic | 3 | 0 | 11 | 11 | 3.67 |
| 13 | Tulsa | 2 | 1 | 6 | 7 | 3.50 |
| 14 | Charlotte | 1 | 0 | 2 | 2 | 2.00 |