2025 American Conference Leaders Passes Defended - Games in August/September Only through 09/13/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Temple | 3 | 3 | 15 | 18 | 6.00 |
| 2 | Tulane | 3 | 5 | 12 | 17 | 5.67 |
| 2 | Memphis | 3 | 4 | 13 | 17 | 5.67 |
| 4 | Army | 2 | 1 | 10 | 11 | 5.50 |
| 5 | East Carolina | 3 | 3 | 13 | 16 | 5.33 |
| 6 | UTSA | 3 | 3 | 11 | 14 | 4.67 |
| 6 | Florida Atlantic | 3 | 0 | 14 | 14 | 4.67 |
| 8 | Navy | 3 | 3 | 10 | 13 | 4.33 |
| 9 | USF | 3 | 3 | 8 | 11 | 3.67 |
| 9 | Rice | 3 | 1 | 10 | 11 | 3.67 |
| 11 | UAB | 3 | 0 | 10 | 10 | 3.33 |
| 12 | Tulsa | 3 | 3 | 6 | 9 | 3.00 |
| 13 | North Texas | 3 | 4 | 3 | 7 | 2.33 |
| 13 | Charlotte | 3 | 0 | 7 | 7 | 2.33 |