2025 American Conference Leaders Passes Defended - Games in October Only through 11/01/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 4 | 6 | 16 | 22 | 5.50 |
| 1 | UTSA | 4 | 4 | 18 | 22 | 5.50 |
| 3 | USF | 4 | 6 | 14 | 20 | 5.00 |
| 4 | Navy | 3 | 1 | 11 | 12 | 4.00 |
| 5 | North Texas | 3 | 1 | 10 | 11 | 3.67 |
| 6 | Temple | 4 | 3 | 11 | 14 | 3.50 |
| 6 | East Carolina | 2 | 0 | 7 | 7 | 3.50 |
| 8 | Rice | 4 | 1 | 11 | 12 | 3.00 |
| 8 | Tulsa | 3 | 2 | 7 | 9 | 3.00 |
| 8 | Army | 3 | 2 | 7 | 9 | 3.00 |
| 11 | Tulane | 3 | 0 | 7 | 7 | 2.33 |
| 12 | Charlotte | 4 | 3 | 5 | 8 | 2.00 |
| 12 | Florida Atlantic | 4 | 0 | 8 | 8 | 2.00 |
| 12 | UAB | 3 | 2 | 4 | 6 | 2.00 |