2025 American Conference Leaders Passes Defended - Games on the Road/Neutral Site Only through 12/20/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | East Carolina | 6 | 7 | 24 | 31 | 5.17 |
| 2 | USF | 7 | 9 | 21 | 30 | 4.29 |
| 3 | Army | 7 | 8 | 21 | 29 | 4.14 |
| 4 | Rice | 5 | 2 | 18 | 20 | 4.00 |
| 5 | Memphis | 7 | 4 | 22 | 26 | 3.71 |
| 6 | UTSA | 6 | 1 | 20 | 21 | 3.50 |
| 7 | Tulsa | 6 | 3 | 16 | 19 | 3.17 |
| 8 | Tulane | 7 | 2 | 20 | 22 | 3.14 |
| 9 | Florida Atlantic | 6 | 1 | 17 | 18 | 3.00 |
| 9 | Charlotte | 5 | 5 | 10 | 15 | 3.00 |
| 11 | North Texas | 6 | 4 | 12 | 16 | 2.67 |
| 11 | Navy | 6 | 2 | 14 | 16 | 2.67 |
| 13 | Temple | 6 | 2 | 13 | 15 | 2.50 |
| 14 | UAB | 6 | 3 | 9 | 12 | 2.00 |