2025 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Virginia | 1 | 2 | 9 | 2 | 13 | 13.0 |
| 2 | Stanford | 1 | 3 | 13 | 4 | 20 | 20.0 |
| 2 | North Carolina | 1 | 3 | 16 | 2 | 21 | 21.0 |
| 4 | NC State | 1 | 4 | 13 | 1 | 18 | 18.0 |
| 5 | Pittsburgh | 1 | 5 | 7 | 1 | 13 | 13.0 |
| 6 | Miami (FL) | 1 | 7 | 9 | 2 | 18 | 18.0 |
| 6 | Syracuse | 1 | 7 | 11 | 2 | 20 | 20.0 |
| 8 | Clemson | 1 | 8 | 8 | 0 | 16 | 16.0 |
| 9 | Wake Forest | 1 | 10 | 6 | 2 | 18 | 18.0 |
| 10 | Louisville | 1 | 12 | 5 | 2 | 19 | 19.0 |