2025 Atlantic Coast Conference Leaders Opponent First Downs - Games in October Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | NC State | 3 | 13 | 41 | 12 | 66 | 22.0 |
| 2 | Duke | 2 | 14 | 21 | 6 | 41 | 20.5 |
| 3 | Clemson | 3 | 18 | 31 | 6 | 55 | 18.3 |
| 4 | Louisville | 3 | 20 | 27 | 2 | 49 | 16.3 |
| 4 | Florida State | 3 | 20 | 27 | 9 | 56 | 18.7 |
| 4 | SMU | 4 | 20 | 52 | 6 | 78 | 19.5 |
| 4 | Virginia | 3 | 20 | 36 | 8 | 64 | 21.3 |
| 8 | Wake Forest | 3 | 21 | 17 | 8 | 46 | 15.3 |
| 9 | Miami (FL) | 3 | 22 | 31 | 5 | 58 | 19.3 |
| 10 | Virginia Tech | 3 | 24 | 33 | 9 | 66 | 22.0 |
| 11 | Pittsburgh | 4 | 25 | 30 | 5 | 60 | 15.0 |
| 12 | Georgia Tech | 3 | 26 | 34 | 3 | 63 | 21.0 |
| 13 | Stanford | 3 | 27 | 34 | 3 | 64 | 21.3 |
| 14 | North Carolina | 4 | 28 | 33 | 9 | 70 | 17.5 |
| 15 | California | 3 | 33 | 26 | 7 | 66 | 22.0 |
| 16 | Boston College | 4 | 38 | 50 | 7 | 95 | 23.8 |
| 17 | Syracuse | 4 | 40 | 39 | 6 | 85 | 21.3 |