2025 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. FBS Power 5 Conference Teams Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 5 | 30 | 48 | 7 | 85 | 17.0 |
| 2 | Louisville | 5 | 32 | 41 | 6 | 79 | 15.8 |
| 3 | NC State | 6 | 42 | 80 | 13 | 135 | 22.5 |
| 4 | Duke | 6 | 46 | 74 | 19 | 139 | 23.2 |
| 5 | Pittsburgh | 7 | 47 | 71 | 11 | 129 | 18.4 |
| 5 | Clemson | 7 | 47 | 80 | 17 | 144 | 20.6 |
| 7 | North Carolina | 6 | 49 | 61 | 12 | 122 | 20.3 |
| 7 | SMU | 7 | 49 | 96 | 12 | 157 | 22.4 |
| 9 | Florida State | 6 | 50 | 56 | 14 | 120 | 20.0 |
| 10 | Wake Forest | 6 | 51 | 47 | 17 | 115 | 19.2 |
| 11 | Boston College | 6 | 52 | 66 | 16 | 134 | 22.3 |
| 12 | Virginia | 7 | 53 | 77 | 9 | 139 | 19.9 |
| 13 | Georgia Tech | 7 | 57 | 78 | 10 | 145 | 20.7 |
| 14 | Virginia Tech | 7 | 59 | 70 | 12 | 141 | 20.1 |
| 15 | Stanford | 7 | 60 | 84 | 11 | 155 | 22.1 |
| 16 | California | 7 | 67 | 66 | 14 | 147 | 21.0 |
| 17 | Syracuse | 7 | 70 | 78 | 11 | 159 | 22.7 |