2025 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. Non-Conference Teams Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Virginia | 3 | 12 | 23 | 3 | 38 | 12.7 |
| 1 | Florida State | 3 | 12 | 21 | 6 | 39 | 13.0 |
| 3 | NC State | 3 | 13 | 35 | 7 | 55 | 18.3 |
| 4 | Stanford | 3 | 15 | 41 | 9 | 65 | 21.7 |
| 5 | Clemson | 2 | 16 | 21 | 4 | 41 | 20.5 |
| 6 | Miami (FL) | 4 | 19 | 28 | 7 | 54 | 13.5 |
| 7 | Pittsburgh | 3 | 22 | 21 | 6 | 49 | 16.3 |
| 7 | Boston College | 4 | 22 | 43 | 11 | 76 | 19.0 |
| 7 | Georgia Tech | 3 | 22 | 26 | 10 | 58 | 19.3 |
| 7 | Duke | 3 | 22 | 33 | 6 | 61 | 20.3 |
| 11 | Wake Forest | 3 | 23 | 25 | 9 | 57 | 19.0 |
| 12 | Louisville | 3 | 24 | 14 | 5 | 43 | 14.3 |
| 13 | California | 4 | 26 | 33 | 7 | 66 | 16.5 |
| 14 | Syracuse | 3 | 27 | 34 | 6 | 67 | 22.3 |
| 14 | SMU | 4 | 27 | 54 | 11 | 92 | 23.0 |
| 16 | Virginia Tech | 4 | 31 | 38 | 7 | 76 | 19.0 |
| 17 | North Carolina | 4 | 32 | 48 | 8 | 88 | 22.0 |