2025 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. Unranked Teams Only (AP Poll) through 09/05/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Virginia | 1 | 2 | 9 | 2 | 13 | 13.0 |
| 2 | Pittsburgh | 1 | 3 | 4 | 1 | 8 | 8.0 |
| 2 | Boston College | 1 | 3 | 9 | 1 | 13 | 13.0 |
| 2 | Stanford | 1 | 3 | 13 | 4 | 20 | 20.0 |
| 5 | SMU | 1 | 4 | 12 | 1 | 17 | 17.0 |
| 5 | NC State | 1 | 4 | 13 | 1 | 18 | 18.0 |
| 7 | Florida State | 1 | 5 | 11 | 2 | 18 | 18.0 |
| 8 | Miami (FL) | 1 | 7 | 9 | 2 | 18 | 18.0 |
| 8 | Georgia Tech | 1 | 7 | 9 | 3 | 19 | 19.0 |
| 8 | California | 1 | 7 | 10 | 2 | 19 | 19.0 |
| 11 | Duke | 1 | 8 | 6 | 0 | 14 | 14.0 |
| 11 | Virginia Tech | 1 | 8 | 8 | 0 | 16 | 16.0 |
| 11 | Clemson | 1 | 8 | 13 | 4 | 25 | 25.0 |
| 14 | Wake Forest | 1 | 10 | 6 | 2 | 18 | 18.0 |
| 15 | Syracuse | 1 | 12 | 9 | 1 | 22 | 22.0 |
| 15 | North Carolina | 1 | 12 | 16 | 1 | 29 | 29.0 |
| 17 | Louisville | 2 | 16 | 8 | 5 | 29 | 14.5 |