2025 Atlantic Coast Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 09/11/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 1 | 93 | 221 | 58 | 314 | 5.41 | 314.0 |
| 2 | Virginia Tech | 1 | 119 | 209 | 56 | 328 | 5.86 | 328.0 |
| 3 | Florida State | 1 | 87 | 254 | 72 | 341 | 4.74 | 341.0 |
| 4 | Clemson | 1 | 108 | 248 | 70 | 356 | 5.09 | 356.0 |
| 5 | Duke | 1 | 123 | 296 | 73 | 419 | 5.74 | 419.0 |
| 6 | Syracuse | 1 | 246 | 247 | 68 | 493 | 7.25 | 493.0 |