2025 Atlantic Coast Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/09/2026
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 5 | 599 | 611 | 301 | 1210 | 4.02 | 242.0 |
| 2 | Virginia | 4 | 444 | 651 | 233 | 1095 | 4.70 | 273.8 |
| 3 | Miami (FL) | 7 | 560 | 1474 | 423 | 2034 | 4.81 | 290.6 |
| 4 | Florida State | 4 | 507 | 677 | 245 | 1184 | 4.83 | 296.0 |
| 5 | Pittsburgh | 5 | 498 | 997 | 343 | 1495 | 4.36 | 299.0 |
| 6 | California | 5 | 475 | 1081 | 313 | 1556 | 4.97 | 311.2 |
| 7 | Wake Forest | 5 | 507 | 1055 | 377 | 1562 | 4.14 | 312.4 |
| 8 | Georgia Tech | 5 | 737 | 907 | 348 | 1644 | 4.72 | 328.8 |
| 9 | North Carolina | 4 | 546 | 832 | 272 | 1378 | 5.07 | 344.5 |
| 10 | NC State | 4 | 389 | 1000 | 280 | 1389 | 4.96 | 347.3 |
| 11 | Clemson | 5 | 430 | 1317 | 340 | 1747 | 5.14 | 349.4 |
| 12 | Boston College | 4 | 417 | 1044 | 243 | 1461 | 6.01 | 365.3 |
| 13 | Virginia Tech | 4 | 630 | 855 | 225 | 1485 | 6.60 | 371.3 |
| 14 | Stanford | 4 | 491 | 1195 | 278 | 1686 | 6.06 | 421.5 |
| 15 | Syracuse | 4 | 824 | 891 | 268 | 1715 | 6.40 | 428.8 |
| 16 | Duke | 5 | 842 | 1369 | 344 | 2211 | 6.43 | 442.2 |
| 17 | SMU | 5 | 635 | 1603 | 393 | 2238 | 5.69 | 447.6 |