2025 Atlantic Coast Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 10/24/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 4 | 305 | 673 | 229 | 978 | 4.27 | 244.5 |
| 2 | Louisville | 3 | 390 | 344 | 181 | 734 | 4.06 | 244.7 |
| 3 | Florida State | 3 | 235 | 509 | 176 | 744 | 4.23 | 248.0 |
| 4 | Virginia | 3 | 285 | 550 | 178 | 835 | 4.69 | 278.3 |
| 5 | Wake Forest | 3 | 326 | 528 | 232 | 854 | 3.68 | 284.7 |
| 6 | Pittsburgh | 3 | 251 | 608 | 216 | 859 | 3.98 | 286.3 |
| 7 | California | 4 | 382 | 779 | 241 | 1161 | 4.82 | 290.3 |
| 8 | Georgia Tech | 3 | 447 | 512 | 218 | 959 | 4.40 | 319.7 |
| 9 | Clemson | 2 | 186 | 471 | 133 | 657 | 4.94 | 328.5 |
| 10 | Boston College | 3 | 258 | 745 | 188 | 1003 | 5.34 | 334.3 |
| 11 | North Carolina | 4 | 546 | 832 | 272 | 1378 | 5.07 | 344.5 |
| 12 | NC State | 3 | 240 | 846 | 210 | 1086 | 5.17 | 362.0 |
| 13 | Virginia Tech | 4 | 630 | 855 | 225 | 1485 | 6.60 | 371.3 |
| 14 | Duke | 3 | 442 | 678 | 198 | 1120 | 5.66 | 373.3 |
| 15 | Stanford | 3 | 304 | 858 | 204 | 1162 | 5.70 | 387.3 |
| 16 | Syracuse | 3 | 495 | 822 | 229 | 1317 | 5.75 | 439.0 |
| 17 | SMU | 4 | 459 | 1338 | 314 | 1797 | 5.72 | 449.3 |