2025 Atlantic Coast Conference Leaders Total Defense - Games vs. Conference Teams Only through 10/02/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Virginia Tech | 1 | 59 | 240 | 66 | 299 | 4.53 | 299.0 |
| 2 | Louisville | 1 | 80 | 259 | 55 | 339 | 6.16 | 339.0 |
| 3 | California | 1 | 178 | 197 | 58 | 375 | 6.47 | 375.0 |
| 4 | Boston College | 2 | 331 | 440 | 130 | 771 | 5.93 | 385.5 |
| 5 | Pittsburgh | 1 | 53 | 339 | 85 | 392 | 4.61 | 392.0 |
| 6 | Clemson | 2 | 301 | 490 | 147 | 791 | 5.38 | 395.5 |
| 7 | Wake Forest | 2 | 368 | 449 | 161 | 817 | 5.07 | 408.5 |
| 8 | Georgia Tech | 2 | 384 | 440 | 132 | 824 | 6.24 | 412.0 |
| 9 | NC State | 4 | 694 | 955 | 260 | 1649 | 6.34 | 412.3 |
| 10 | Virginia | 3 | 507 | 744 | 199 | 1251 | 6.29 | 417.0 |
| 11 | Duke | 2 | 256 | 593 | 138 | 849 | 6.15 | 424.5 |
| 12 | Florida State | 1 | 211 | 229 | 84 | 440 | 5.24 | 440.0 |
| 13 | Stanford | 2 | 262 | 717 | 141 | 979 | 6.94 | 489.5 |
| 14 | Syracuse | 2 | 375 | 631 | 148 | 1006 | 6.80 | 503.0 |