2025 Atlantic Coast Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 12/06/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina | 1 | 59 | 200 | 69 | 259 | 3.75 | 259.0 |
| 2 | Miami (FL) | 1 | 93 | 221 | 58 | 314 | 5.41 | 314.0 |
| 3 | Clemson | 1 | 147 | 211 | 70 | 358 | 5.11 | 358.0 |
| 4 | SMU | 1 | 159 | 274 | 78 | 433 | 5.55 | 433.0 |
| 5 | Georgia Tech | 1 | 190 | 70 | 67 | 260 | 3.88 | 260.0 |
| 6 | California | 1 | 194 | 262 | 80 | 456 | 5.70 | 456.0 |
| 7 | Louisville | 3 | 277 | 557 | 200 | 834 | 4.17 | 278.0 |
| 8 | Wake Forest | 2 | 326 | 412 | 149 | 738 | 4.95 | 369.0 |
| 9 | Florida State | 3 | 395 | 724 | 215 | 1119 | 5.20 | 373.0 |
| 10 | Boston College | 2 | 416 | 670 | 131 | 1086 | 8.29 | 543.0 |
| 11 | Pittsburgh | 3 | 436 | 745 | 213 | 1181 | 5.54 | 393.7 |
| 12 | Duke | 4 | 679 | 1007 | 266 | 1686 | 6.34 | 421.5 |
| 13 | Syracuse | 3 | 691 | 632 | 164 | 1323 | 8.07 | 441.0 |
| 14 | Stanford | 4 | 749 | 1101 | 290 | 1850 | 6.38 | 462.5 |
| 15 | NC State | 4 | 765 | 1374 | 286 | 2139 | 7.48 | 534.8 |
| 16 | Virginia Tech | 4 | 810 | 959 | 269 | 1769 | 6.58 | 442.3 |