2025 Big 12 Conference Leaders Passes Defended - Games vs. Conference Teams Only through 01/19/2026
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Arizona | 10 | 14 | 46 | 60 | 6.00 |
| 2 | Kansas State | 10 | 13 | 43 | 56 | 5.60 |
| 3 | Texas Tech | 10 | 12 | 51 | 63 | 6.30 |
| 3 | BYU | 10 | 12 | 34 | 46 | 4.60 |
| 5 | Utah | 9 | 10 | 39 | 49 | 5.44 |
| 6 | Houston | 9 | 9 | 38 | 47 | 5.22 |
| 6 | TCU | 9 | 9 | 29 | 38 | 4.22 |
| 8 | Iowa State | 9 | 7 | 34 | 41 | 4.56 |
| 8 | West Virginia | 9 | 7 | 29 | 36 | 4.00 |
| 10 | Arizona State | 9 | 6 | 41 | 47 | 5.22 |
| 11 | Baylor | 9 | 5 | 29 | 34 | 3.78 |
| 11 | UCF | 9 | 5 | 29 | 34 | 3.78 |
| 11 | Oklahoma State | 9 | 5 | 28 | 33 | 3.67 |
| 14 | Colorado | 9 | 4 | 27 | 31 | 3.44 |
| 15 | Kansas | 9 | 2 | 38 | 40 | 4.44 |
| 15 | Cincinnati | 9 | 2 | 32 | 34 | 3.78 |