2025 Big 12 Conference Leaders Passes Defended - Games vs. Conference Teams Only through 09/18/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Arizona | 1 | 0 | 8 | 8 | 8.00 |
| 2 | Kansas State | 2 | 1 | 12 | 13 | 6.50 |
| 3 | Houston | 1 | 2 | 2 | 4 | 4.00 |
| 3 | Iowa State | 1 | 0 | 4 | 4 | 4.00 |
| 5 | Colorado | 1 | 0 | 2 | 2 | 2.00 |