2025 Big 12 Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 10/16/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Arizona | 2 | 5 | 9 | 14 | 7.00 |
| 2 | Colorado | 3 | 2 | 16 | 18 | 6.00 |
| 2 | Arizona State | 3 | 1 | 17 | 18 | 6.00 |
| 4 | Houston | 3 | 3 | 14 | 17 | 5.67 |
| 5 | UCF | 3 | 4 | 12 | 16 | 5.33 |
| 6 | Texas Tech | 3 | 4 | 11 | 15 | 5.00 |
| 7 | Iowa State | 3 | 4 | 10 | 14 | 4.67 |
| 7 | West Virginia | 3 | 4 | 10 | 14 | 4.67 |
| 9 | Baylor | 3 | 4 | 8 | 12 | 4.00 |
| 9 | Utah | 3 | 4 | 8 | 12 | 4.00 |
| 9 | Kansas | 3 | 2 | 10 | 12 | 4.00 |
| 12 | BYU | 3 | 4 | 7 | 11 | 3.67 |
| 13 | TCU | 3 | 3 | 7 | 10 | 3.33 |
| 14 | Oklahoma State | 3 | 1 | 6 | 7 | 2.33 |
| 15 | Kansas State | 2 | 0 | 4 | 4 | 2.00 |
| 16 | Cincinnati | 3 | 0 | 5 | 5 | 1.67 |