2025 Big 12 Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 10/14/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | BYU | 4 | 511 | 615 | 253 | 1126 | 4.45 | 281.5 |
| 2 | Texas Tech | 4 | 259 | 879 | 269 | 1138 | 4.23 | 284.5 |
| 3 | Arizona | 4 | 563 | 617 | 261 | 1180 | 4.52 | 295.0 |
| 4 | UCF | 4 | 565 | 748 | 234 | 1313 | 5.61 | 328.3 |
| 5 | Utah | 4 | 667 | 656 | 261 | 1323 | 5.07 | 330.8 |
| 6 | Arizona State | 4 | 459 | 924 | 238 | 1383 | 5.81 | 345.8 |
| 7 | Houston | 4 | 537 | 930 | 281 | 1467 | 5.22 | 366.8 |
| 8 | TCU | 5 | 616 | 1168 | 333 | 1784 | 5.36 | 356.8 |
| 9 | West Virginia | 4 | 695 | 1090 | 283 | 1785 | 6.31 | 446.3 |
| 10 | Iowa State | 5 | 748 | 1078 | 315 | 1826 | 5.80 | 365.2 |
| 11 | Cincinnati | 4 | 609 | 1224 | 308 | 1833 | 5.95 | 458.3 |
| 12 | Kansas State | 5 | 739 | 1279 | 345 | 2018 | 5.85 | 403.6 |
| 13 | Colorado | 5 | 1067 | 1024 | 348 | 2091 | 6.01 | 418.2 |
| 14 | Oklahoma State | 4 | 742 | 1464 | 291 | 2206 | 7.58 | 551.5 |
| 15 | Baylor | 5 | 968 | 1259 | 375 | 2227 | 5.94 | 445.4 |
| 16 | Kansas | 5 | 1228 | 1173 | 383 | 2401 | 6.27 | 480.2 |