2025 Big 12 Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 11/04/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UCF | 6 | 846 | 1094 | 390 | 1940 | 4.97 | 323.3 |
| 2 | BYU | 6 | 921 | 1170 | 396 | 2091 | 5.28 | 348.5 |
| 3 | Arizona | 6 | 924 | 951 | 406 | 1875 | 4.62 | 312.5 |
| 4 | Arizona State | 7 | 901 | 1478 | 442 | 2379 | 5.38 | 339.9 |
| 5 | Iowa State | 7 | 1141 | 1562 | 449 | 2703 | 6.02 | 386.1 |
| 6 | Utah | 7 | 1113 | 1145 | 458 | 2258 | 4.93 | 322.6 |
| 7 | Texas Tech | 7 | 555 | 1484 | 478 | 2039 | 4.27 | 291.3 |
| 7 | Oklahoma State | 7 | 1205 | 2140 | 478 | 3345 | 7.00 | 477.9 |
| 9 | Houston | 7 | 993 | 1684 | 480 | 2677 | 5.58 | 382.4 |
| 10 | Colorado | 7 | 1693 | 1402 | 487 | 3095 | 6.36 | 442.1 |
| 11 | TCU | 7 | 778 | 1787 | 495 | 2565 | 5.18 | 366.4 |
| 12 | West Virginia | 7 | 1128 | 1978 | 497 | 3106 | 6.25 | 443.7 |
| 13 | Kansas State | 7 | 1036 | 1665 | 498 | 2701 | 5.42 | 385.9 |
| 13 | Kansas | 7 | 1440 | 1648 | 498 | 3088 | 6.20 | 441.1 |
| 15 | Cincinnati | 7 | 1233 | 1723 | 517 | 2956 | 5.72 | 422.3 |
| 16 | Baylor | 8 | 1503 | 1752 | 571 | 3255 | 5.70 | 406.9 |