2025 Big 12 Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 10/14/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 1 | 101 | 162 | 69 | 263 | 3.81 | 263.0 |
| 2 | UCF | 1 | 115 | 191 | 48 | 306 | 6.38 | 306.0 |
| 3 | Cincinnati | 1 | 110 | 243 | 78 | 353 | 4.53 | 353.0 |
| 4 | Arizona State | 1 | 276 | 136 | 55 | 412 | 7.49 | 412.0 |
| 5 | Arizona | 1 | 258 | 172 | 80 | 430 | 5.38 | 430.0 |
| 6 | Iowa State | 1 | 260 | 214 | 59 | 474 | 8.03 | 474.0 |
| 7 | Utah | 1 | 173 | 311 | 72 | 484 | 6.72 | 484.0 |
| 8 | Houston | 1 | 207 | 345 | 90 | 552 | 6.13 | 552.0 |
| 9 | Oklahoma State | 1 | 312 | 319 | 62 | 631 | 10.18 | 631.0 |
| 10 | Colorado | 2 | 528 | 322 | 133 | 850 | 6.39 | 425.0 |
| 11 | West Virginia | 2 | 407 | 641 | 144 | 1048 | 7.28 | 524.0 |
| 12 | Kansas | 3 | 848 | 855 | 235 | 1703 | 7.25 | 567.7 |