2025 Big 12 Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 11/28/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 9 | 674 | 1850 | 605 | 2524 | 4.17 | 280.4 |
| 2 | Arizona State | 10 | 1192 | 2282 | 670 | 3474 | 5.19 | 347.4 |
| 3 | BYU | 9 | 1272 | 1872 | 589 | 3144 | 5.34 | 349.3 |
| 3 | Houston | 9 | 1272 | 2113 | 609 | 3385 | 5.56 | 376.1 |
| 5 | West Virginia | 9 | 1302 | 2484 | 637 | 3786 | 5.94 | 420.7 |
| 6 | TCU | 10 | 1320 | 2355 | 701 | 3675 | 5.24 | 367.5 |
| 7 | UCF | 9 | 1365 | 1735 | 599 | 3100 | 5.18 | 344.4 |
| 8 | Iowa State | 9 | 1386 | 2072 | 579 | 3458 | 5.97 | 384.2 |
| 9 | Oklahoma State | 9 | 1437 | 2588 | 597 | 4025 | 6.74 | 447.2 |
| 10 | Kansas State | 9 | 1475 | 2150 | 649 | 3625 | 5.59 | 402.8 |
| 11 | Arizona | 10 | 1565 | 1580 | 663 | 3145 | 4.74 | 314.5 |
| 12 | Cincinnati | 9 | 1679 | 2144 | 664 | 3823 | 5.76 | 424.8 |
| 13 | Kansas | 10 | 1987 | 2300 | 687 | 4287 | 6.24 | 428.7 |
| 14 | Utah | 10 | 2008 | 1864 | 693 | 3872 | 5.59 | 387.2 |
| 15 | Baylor | 10 | 2055 | 2038 | 689 | 4093 | 5.94 | 409.3 |
| 16 | Colorado | 9 | 2215 | 1829 | 639 | 4044 | 6.33 | 449.3 |