2025 Big 12 Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 12/20/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Arizona | 10 | 1565 | 1580 | 663 | 3145 | 4.74 | 314.5 |
| 2 | Utah | 10 | 2008 | 1864 | 693 | 3872 | 5.59 | 387.2 |
| 3 | Colorado | 10 | 2421 | 1944 | 699 | 4365 | 6.24 | 436.5 |
| 4 | UCF | 10 | 1483 | 2024 | 664 | 3507 | 5.28 | 350.7 |
| 5 | Texas Tech | 11 | 774 | 2130 | 718 | 2904 | 4.04 | 264.0 |
| 6 | Baylor | 11 | 2271 | 2239 | 768 | 4510 | 5.87 | 410.0 |
| 7 | Iowa State | 10 | 1413 | 2274 | 636 | 3687 | 5.80 | 368.7 |
| 8 | Arizona State | 10 | 1192 | 2282 | 670 | 3474 | 5.19 | 347.4 |
| 9 | Kansas | 10 | 1987 | 2300 | 687 | 4287 | 6.24 | 428.7 |
| 10 | Kansas State | 10 | 1626 | 2322 | 721 | 3948 | 5.48 | 394.8 |
| 11 | BYU | 11 | 1473 | 2341 | 723 | 3814 | 5.28 | 346.7 |
| 12 | Houston | 10 | 1384 | 2422 | 681 | 3806 | 5.59 | 380.6 |
| 13 | Cincinnati | 10 | 1917 | 2450 | 738 | 4367 | 5.92 | 436.7 |
| 14 | TCU | 11 | 1435 | 2637 | 753 | 4072 | 5.41 | 370.2 |
| 15 | Oklahoma State | 10 | 1670 | 2701 | 664 | 4371 | 6.58 | 437.1 |
| 16 | West Virginia | 10 | 1490 | 2868 | 731 | 4358 | 5.96 | 435.8 |