2025 Conference USA Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/08/2026
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | FIU | 11 | 100 | 118 | 17 | 235 | 21.4 |
| 2 | New Mexico State | 10 | 86 | 116 | 18 | 220 | 22.0 |
| 3 | Liberty | 11 | 110 | 98 | 19 | 227 | 20.6 |
| 4 | Sam Houston State | 10 | 97 | 119 | 21 | 237 | 23.7 |
| 5 | Missouri State | 10 | 79 | 101 | 22 | 202 | 20.2 |
| 6 | Delaware | 10 | 67 | 122 | 23 | 212 | 21.2 |
| 7 | Jacksonville State | 12 | 108 | 122 | 24 | 254 | 21.2 |
| 7 | Middle Tennessee State | 10 | 82 | 113 | 24 | 219 | 21.9 |
| 9 | UTEP | 10 | 78 | 108 | 25 | 211 | 21.1 |
| 9 | Kennesaw State | 11 | 101 | 107 | 25 | 233 | 21.2 |
| 11 | Louisiana Tech | 10 | 69 | 107 | 29 | 205 | 20.5 |
| 12 | Western Kentucky | 11 | 81 | 115 | 33 | 229 | 20.8 |