2025 Conference USA Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 1 | 7 | 4 | 1 | 12 | 12.0 |
| 2 | Western Kentucky | 2 | 14 | 17 | 4 | 35 | 17.5 |
| 3 | UTEP | 1 | 7 | 10 | 1 | 18 | 18.0 |
| 3 | Liberty | 1 | 15 | 3 | 0 | 18 | 18.0 |
| 5 | Jacksonville State | 1 | 10 | 10 | 0 | 20 | 20.0 |
| 6 | Sam Houston State | 3 | 18 | 47 | 5 | 70 | 23.3 |
| 7 | New Mexico State | 1 | 8 | 14 | 3 | 25 | 25.0 |