2025 Conference USA Leaders Opponent First Downs - Games vs. Non-Conference Teams Only through 09/06/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Liberty | 1 | 6 | 9 | 0 | 15 | 15.0 |
| 2 | FIU | 2 | 17 | 19 | 1 | 37 | 18.5 |
| 3 | Jacksonville State | 1 | 9 | 12 | 2 | 23 | 23.0 |
| 4 | UTEP | 2 | 12 | 22 | 3 | 37 | 18.5 |
| 4 | Middle Tennessee State | 2 | 15 | 22 | 3 | 40 | 20.0 |
| 4 | Sam Houston State | 2 | 14 | 27 | 3 | 44 | 22.0 |
| 4 | Kennesaw State | 2 | 22 | 23 | 3 | 48 | 24.0 |
| 8 | Delaware | 2 | 17 | 21 | 4 | 42 | 21.0 |
| 9 | Missouri State | 2 | 15 | 19 | 5 | 39 | 19.5 |
| 9 | New Mexico State | 2 | 11 | 25 | 5 | 41 | 20.5 |
| 11 | Western Kentucky | 2 | 18 | 13 | 7 | 38 | 19.0 |
| 12 | Louisiana Tech | 2 | 17 | 20 | 8 | 45 | 22.5 |