2025 Conference USA Leaders Opponent First Downs - Games vs. Unranked Teams Only (AP Poll) through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Liberty | 8 | 74 | 68 | 7 | 149 | 18.6 |
| 2 | FIU | 8 | 68 | 82 | 12 | 162 | 20.3 |
| 2 | Delaware | 8 | 62 | 100 | 12 | 174 | 21.8 |
| 4 | Kennesaw State | 7 | 52 | 74 | 13 | 139 | 19.9 |
| 4 | Sam Houston State | 7 | 70 | 82 | 13 | 165 | 23.6 |
| 6 | Middle Tennessee State | 8 | 69 | 79 | 15 | 163 | 20.4 |
| 7 | UTEP | 7 | 52 | 63 | 16 | 131 | 18.7 |
| 7 | Jacksonville State | 8 | 68 | 79 | 16 | 163 | 20.4 |
| 7 | New Mexico State | 8 | 62 | 97 | 16 | 175 | 21.9 |
| 10 | Missouri State | 7 | 46 | 77 | 17 | 140 | 20.0 |
| 11 | Louisiana Tech | 8 | 54 | 90 | 21 | 165 | 20.6 |
| 12 | Western Kentucky | 9 | 69 | 83 | 29 | 181 | 20.1 |