2025 Conference USA Leaders Rushing Defense - Games vs. Conference Teams Only through 11/01/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 4 | 114 | 442 | 3.88 | 3 | 28.50 | 110.50 |
| 1 | Jacksonville State | 4 | 114 | 467 | 4.10 | 6 | 28.50 | 116.75 |
| 3 | FIU | 4 | 132 | 676 | 5.12 | 7 | 33.00 | 169.00 |
| 4 | Liberty | 4 | 139 | 616 | 4.43 | 7 | 34.75 | 154.00 |
| 5 | Louisiana Tech | 5 | 144 | 671 | 4.66 | 5 | 28.80 | 134.20 |
| 6 | Middle Tennessee State | 4 | 151 | 447 | 2.96 | 2 | 37.75 | 111.75 |
| 7 | Kennesaw State | 4 | 157 | 648 | 4.13 | 5 | 39.25 | 162.00 |
| 8 | UTEP | 4 | 171 | 564 | 3.30 | 4 | 42.75 | 141.00 |
| 9 | Delaware | 5 | 173 | 908 | 5.25 | 12 | 34.60 | 181.60 |
| 10 | New Mexico State | 5 | 191 | 790 | 4.14 | 6 | 38.20 | 158.00 |
| 11 | Western Kentucky | 6 | 201 | 932 | 4.64 | 8 | 33.50 | 155.33 |
| 12 | Sam Houston State | 5 | 202 | 1171 | 5.80 | 16 | 40.40 | 234.20 |