2025 Conference USA Leaders Rushing Defense - Games vs. Non-Conference Teams Only through 09/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Sam Houston State | 2 | 67 | 278 | 4.15 | 2 | 33.50 | 139.00 |
| 2 | Liberty | 2 | 68 | 342 | 5.03 | 2 | 34.00 | 171.00 |
| 3 | New Mexico State | 2 | 72 | 209 | 2.90 | 1 | 36.00 | 104.50 |
| 4 | Louisiana Tech | 2 | 78 | 254 | 3.26 | 1 | 39.00 | 127.00 |
| 5 | Jacksonville State | 2 | 79 | 327 | 4.14 | 3 | 39.50 | 163.50 |
| 5 | Western Kentucky | 2 | 79 | 460 | 5.82 | 2 | 39.50 | 230.00 |
| 7 | FIU | 3 | 92 | 449 | 4.88 | 3 | 30.67 | 149.67 |
| 8 | Missouri State | 3 | 97 | 591 | 6.09 | 11 | 32.33 | 197.00 |
| 9 | Delaware | 3 | 112 | 505 | 4.51 | 6 | 37.33 | 168.33 |
| 10 | Middle Tennessee State | 3 | 113 | 506 | 4.48 | 5 | 37.67 | 168.67 |
| 11 | Kennesaw State | 3 | 124 | 522 | 4.21 | 5 | 41.33 | 174.00 |
| 12 | UTEP | 3 | 129 | 429 | 3.33 | 5 | 43.00 | 143.00 |