2025 Conference USA Leaders Total Defense - Games in November Only through 12/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 657 | 885 | 263 | 1542 | 5.86 | 385.5 |
| 2 | FIU | 4 | 640 | 910 | 299 | 1550 | 5.18 | 387.5 |
| 3 | Western Kentucky | 4 | 643 | 919 | 281 | 1562 | 5.56 | 390.5 |
| 4 | Liberty | 5 | 822 | 1194 | 347 | 2016 | 5.81 | 403.2 |
| 5 | Missouri State | 4 | 818 | 795 | 279 | 1613 | 5.78 | 403.3 |
| 6 | New Mexico State | 5 | 977 | 1150 | 359 | 2127 | 5.92 | 425.4 |
| 7 | Jacksonville State | 4 | 749 | 982 | 289 | 1731 | 5.99 | 432.8 |
| 8 | Delaware | 5 | 841 | 1352 | 325 | 2193 | 6.75 | 438.6 |
| 9 | Middle Tennessee State | 4 | 577 | 1220 | 284 | 1797 | 6.33 | 449.3 |
| 10 | Kennesaw State | 4 | 809 | 996 | 279 | 1805 | 6.47 | 451.3 |
| 11 | UTEP | 4 | 791 | 1098 | 303 | 1889 | 6.23 | 472.3 |
| 12 | Sam Houston State | 4 | 778 | 1183 | 287 | 1961 | 6.83 | 490.3 |