2025 Conference USA Leaders Total Defense - Games in November Only through 11/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 1 | 66 | 112 | 66 | 178 | 2.70 | 178.0 |
| 2 | Kennesaw State | 1 | 75 | 241 | 82 | 316 | 3.85 | 316.0 |
| 3 | FIU | 1 | 33 | 331 | 78 | 364 | 4.67 | 364.0 |
| 4 | Jacksonville State | 1 | 126 | 244 | 69 | 370 | 5.36 | 370.0 |
| 5 | Liberty | 2 | 122 | 630 | 132 | 752 | 5.70 | 376.0 |
| 6 | Missouri State | 1 | 202 | 196 | 78 | 398 | 5.10 | 398.0 |
| 7 | Louisiana Tech | 1 | 95 | 304 | 76 | 399 | 5.25 | 399.0 |
| 8 | Middle Tennessee State | 1 | 144 | 257 | 66 | 401 | 6.08 | 401.0 |
| 9 | New Mexico State | 2 | 336 | 520 | 153 | 856 | 5.59 | 428.0 |
| 10 | Delaware | 2 | 413 | 481 | 123 | 894 | 7.27 | 447.0 |
| 11 | UTEP | 1 | 275 | 181 | 70 | 456 | 6.51 | 456.0 |
| 12 | Sam Houston State | 1 | 188 | 286 | 82 | 474 | 5.78 | 474.0 |