2021 Conference USA Leaders Sacks - Games vs. FCS (I-AA) Teams Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | North Texas | 1 | 4.0 | 26 | 4.00 |
| 1 | Middle Tennessee State | 1 | 3.0 | 26 | 3.00 |
| 3 | Southern Miss | 1 | 2.0 | 24 | 2.00 |
| 4 | Old Dominion | 1 | 3.0 | 23 | 3.00 |
| 5 | Louisiana Tech | 1 | 3.0 | 19 | 3.00 |
| 6 | Rice | 1 | 2.0 | 16 | 2.00 |
| 6 | UTEP | 1 | 2.0 | 16 | 2.00 |
| 8 | Marshall | 1 | 3.0 | 14 | 3.00 |
| 9 | Florida Atlantic | 1 | 1.0 | 11 | 1.00 |
| 10 | Charlotte | 1 | 2.0 | 7 | 2.00 |
| 10 | Western Kentucky | 1 | 1.0 | 7 | 1.00 |
| 12 | FIU | 1 | 1.0 | 4 | 1.00 |