2021 Conference USA Leaders Sacks - All Games through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | North Texas | 13 | 38.0 | 263 | 2.92 |
| 2 | UTSA | 14 | 33.0 | 254 | 2.36 |
| 3 | Marshall | 13 | 40.0 | 242 | 3.08 |
| 4 | Middle Tennessee | 13 | 32.0 | 237 | 2.46 |
| 5 | Western Kentucky | 14 | 36.0 | 225 | 2.57 |
| 6 | UAB | 13 | 32.0 | 210 | 2.46 |
| 7 | Rice | 12 | 27.0 | 200 | 2.25 |
| 8 | UTEP | 13 | 25.0 | 174 | 1.92 |
| 9 | Old Dominion | 13 | 25.0 | 169 | 1.92 |
| 10 | Southern Mississippi | 12 | 23.0 | 166 | 1.92 |
| 11 | Louisiana Tech | 12 | 20.0 | 143 | 1.67 |
| 12 | Florida Atlantic | 12 | 17.0 | 136 | 1.42 |
| 13 | Charlotte | 12 | 17.0 | 119 | 1.42 |
| 14 | Florida International | 12 | 14.0 | 70 | 1.17 |