2021 Conference USA Leaders Sacks - Games in November Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | North Texas | 4 | 14.0 | 99 | 3.50 |
| 2 | UAB | 4 | 11.0 | 91 | 2.75 |
| 3 | Middle Tennessee | 4 | 10.0 | 89 | 2.50 |
| 4 | Rice | 4 | 11.0 | 78 | 2.75 |
| 5 | Marshall | 4 | 10.0 | 72 | 2.50 |
| 6 | Louisiana Tech | 4 | 9.0 | 69 | 2.25 |
| 7 | Old Dominion | 4 | 11.0 | 66 | 2.75 |
| 8 | Western Kentucky | 4 | 11.0 | 64 | 2.75 |
| 9 | Southern Mississippi | 4 | 8.0 | 61 | 2.00 |
| 10 | Florida Atlantic | 4 | 6.0 | 59 | 1.50 |
| 11 | UTSA | 4 | 6.0 | 45 | 1.50 |
| 12 | Charlotte | 4 | 3.0 | 28 | 0.75 |
| 13 | UTEP | 4 | 3.0 | 23 | 0.75 |
| 14 | Florida International | 4 | 2.0 | 14 | 0.50 |